{"id":61,"date":"2008-04-16T13:53:00","date_gmt":"2008-04-16T13:53:00","guid":{"rendered":"http:\/\/etherwave.wordpress.com\/2008\/04\/16\/holmes-between-biology-and-medicine\/"},"modified":"2008-04-16T13:53:00","modified_gmt":"2008-04-16T13:53:00","slug":"holmes-between-biology-and-medicine","status":"publish","type":"post","link":"https:\/\/rational-action.com\/etherwave\/2008\/04\/16\/holmes-between-biology-and-medicine\/","title":{"rendered":"Holmes&#8217; &#8220;Between Biology and Medicine&#8221;"},"content":{"rendered":"<p>I just gave my 20th century biology lecture yesterday&#8211;not much to report except that I argued that a productive way to approach the subject is to figure out how biology emerges as something independent of medicine, physiology, and chemistry.  I look to the emergence of a full-throttled biochemistry (a chemistry specific to life) situated around 1900: enzymes, understanding proteins, biochemical pathways, and all that.  This merges with the more physiological\/evolutionary genetics with DNA in the new field of molecular biology mid-century.<\/p>\n<p>But, after a bit of scraping, my best guide to all this turned out to be a mightily interesting 1992 book (collecting four 1990 lectures) by Frederic Holmes called (of all titles): &#8220;Between Biology and Medicine: The Formation of Intermediary Metabolism&#8221;.  It sounds very arcane, but turned out to be riveting, because it deals pretty head-on with some of the questions I&#8217;ve been thinking about here.  Basically, Holmes wrote (an absurdly detailed) two-volume book on Hans Krebs, trying to tease out the origins of intermediary metabolism in the 1930s, and, as so-often happens, he had the trap-door open beneath him as he found that intermediary metabolism has &#8220;predecessors&#8221; in the first half of the 1800s.<\/p>\n<p>Now, Holmes is rightly suspicious about this &#8220;predecessors&#8221; question, and ends up tackling some very deep issues about how to write history.  I have a lecture coming up tomorrow on R&amp;D (another very bloggable topic), so I&#8217;m going to leave this here, but I&#8217;m going to come back to this in the next few posts.<\/p>\n<p>Also, Jenny&#8217;s long-awaited online debate thing is due to go forward on the 23rd&#8211;stay tuned!  (seriously)<\/p>\n","protected":false},"excerpt":{"rendered":"<p>I just gave my 20th century biology lecture yesterday&#8211;not much to report except that I argued that a productive way to approach the subject is to figure out how biology emerges as something independent of medicine, physiology, and chemistry. I look to the emergence of a full-throttled biochemistry (a chemistry specific to life) situated around<\/p>\n<p class=\"text-right\"><span class=\"screen-reader-text\">Continue Reading&#8230; Holmes&#8217; &#8220;Between Biology and Medicine&#8221;<\/span><a class=\"btn btn-secondary continue-reading\" href=\"https:\/\/rational-action.com\/etherwave\/2008\/04\/16\/holmes-between-biology-and-medicine\/\">Continue Reading&#8230;<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"nf_dc_page":"","_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[1],"tags":[462],"class_list":["post-61","post","type-post","status-publish","format-standard","hentry","category-uncategorized","tag-frederic-holmes"],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/rational-action.com\/etherwave\/wp-json\/wp\/v2\/posts\/61","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/rational-action.com\/etherwave\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/rational-action.com\/etherwave\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/rational-action.com\/etherwave\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/rational-action.com\/etherwave\/wp-json\/wp\/v2\/comments?post=61"}],"version-history":[{"count":0,"href":"https:\/\/rational-action.com\/etherwave\/wp-json\/wp\/v2\/posts\/61\/revisions"}],"wp:attachment":[{"href":"https:\/\/rational-action.com\/etherwave\/wp-json\/wp\/v2\/media?parent=61"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/rational-action.com\/etherwave\/wp-json\/wp\/v2\/categories?post=61"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/rational-action.com\/etherwave\/wp-json\/wp\/v2\/tags?post=61"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}